The most violent and catastrophic volcanic eruptions on Earth have been triggered by the refilling of a felsic volcanic magma chamber by a hotter more mafic magma. Examples include Vesuvius 79 AD, Krakatau 1883, Pinatubo 1991, and Eyjafjallajokull 2010. Since the first hypothesis, plenty of evidence of magma mixing processes, in all tectonic environments, has accumulated in the literature allowing this natural process to be defined as fundamental petrological processes playing a role in triggering volcanic eruptions, and in the generation of the compositional variability of igneous rocks. Combined with petrographic, mineral chemistry and geochemical investigations, isotopic analyses on volcanic rocks have revealed compositional variations at different length scales pointing to a complex interplay of fractional crystallization, mixing/mingling and crustal contamination during the evolution of several magmatic feeding systems. But to fully understand the dynamics of mixing and mingling processes, that are impossible to observe directly, at a realistically large scale, it is necessary to resort to numerical simulations of the complex interaction dynamics between chemically different magmas.