Heligmosomoides polygyrus:Resistance in Inbred, Outbred, and Selected Mice
Copyright policy )Heligmosomoides polygyrus:Resistance in Inbred, Outbred, and Selected Mice
Mice reared selectively as high- and low- immune responders to reinfection with Heligmosomoides polygyrus showed extremes of resistance and susceptibility after infection when compared to inbred BALB/C, DBA/I, CBA, and SJL/J and outbred Quackenbush (Q) mice. The levels of anti-H. polygyrus total IgG and IgG1, IgG2b, and IgG3 isotype antibodies detected in serum from the seven strains of mice after secondary and the eosinophil leucocyte counts in blood after both primary and secondary infections correlated positively and strongly with the levels of protective immunity developed when evaluated using a resistance index formulated from the infectivity, fecundity, and length of adult worms recovered after infection.
- University of Queensland Australia
- University of Queensland Australia
- University of Queensland Australia
Male, Immunology, 2405 Parasitology, Antibodies, Helminth, Immunoglobulins, Mice, Inbred Strains, Rodent Diseases, Feces, Leukocyte Count, Mice, Sex Factors, Eosinophilia, Animals, Selection, Genetic, Parasite Egg Count, 2403 Immunology, Mice, Inbred BALB C, Nematospiroides dubius, 2725 Infectious Diseases, General Medicine, Immunity, Innate, Fertility, Mice, Inbred DBA, Mice, Inbred CBA, Parasitology, Female
Male, Immunology, 2405 Parasitology, Antibodies, Helminth, Immunoglobulins, Mice, Inbred Strains, Rodent Diseases, Feces, Leukocyte Count, Mice, Sex Factors, Eosinophilia, Animals, Selection, Genetic, Parasite Egg Count, 2403 Immunology, Mice, Inbred BALB C, Nematospiroides dubius, 2725 Infectious Diseases, General Medicine, Immunity, Innate, Fertility, Mice, Inbred DBA, Mice, Inbred CBA, Parasitology, Female
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