zhx-1:A Novel Mouse Homeodomain Protein Containing Two Zinc-Fingers and Five Homeodomains
Copyright policy )zhx-1:A Novel Mouse Homeodomain Protein Containing Two Zinc-Fingers and Five Homeodomains
A cDNA encoding the complete reading frame of a novel homeodomain-containing protein, named zhx-1, has been cloned from a mouse bone marrow stromal cell line. The ORF encodes a protein of 873 amino acids, in which two C2-H2 zinc-fingers and five homeodomains have been identified. These features classify zhx-1 as a member of the ZF class of homeodomain transcription factors, zhx-1 mRNA is widely expressed in adult mouse, although it is preferentially expressed in brain. At least, two homologous mRNAs are present in humans suggesting that zhx-1 is the first member of a novel subclass of homeodomain factors.
Homeodomain Proteins, DNA, Complementary, Base Sequence, Sequence Homology, Amino Acid, Molecular Sequence Data, Zinc Fingers, Cell Line, Mice, Open Reading Frames, Animals, Amino Acid Sequence, RNA, Messenger, Transcription Factors
Homeodomain Proteins, DNA, Complementary, Base Sequence, Sequence Homology, Amino Acid, Molecular Sequence Data, Zinc Fingers, Cell Line, Mice, Open Reading Frames, Animals, Amino Acid Sequence, RNA, Messenger, Transcription Factors
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