Chlorogenic Acid as a Natural Scavenger for Hypochlorous Acid

descriptionPublicationkeyboard_double_arrow_right Article 01 Dec 1995 English Publisher:Elsevier BVJournal:Biochemical and Biophysical Research Communications, volume 217, pages 972-978 (issn: 0006-291X,

Copyright policy )

Authors: Y, Kono; H, Shibata; Y, Kodama; A, Ueda; Y, Sawa;

doi: 10.1006/bbrc.1995.2865

pmid: 8554623

Chlorogenic Acid as a Natural Scavenger for Hypochlorous Acid

- Summary
- Subjects
- Metrics

Abstract

The effect of chlorogenic acid (CGA) on the killing of Escherichia coli by hypochlorous acid (HOCI) was examined. CGA prevented E. coli from bactericidal action of HOCI in a concentration-dependent manner. HOCI reacted rapidly with CGA. By comparison with the one- and two-electron oxidation products produced by peroxidase and phenolase reactions, respectively, the main product was identified as o-quinone of CGA via the formation of o-semiquinone of CGA as an intermediate The quinone form of CGA reacted further with HOCI to yield unstable product(s).

Related Organizations

Shimane University
Japan
Tottori University
Japan

Keywords

Blood Bactericidal Activity, Free Radicals, Spectrum Analysis, Escherichia coli, Quinones, Chlorogenic Acid, Oxidation-Reduction, Hypochlorous Acid

Impact byBIP!

	selected citations These citations are derived from selected sources. This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	37
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Top 10%
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Top 10%
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Top 10%