Cloning and Expression of a cDNA-Encoding the Homologue of Ran/TC4 GTP-Binding Protein from Plasmodium falciparum
Copyright policy )Cloning and Expression of a cDNA-Encoding the Homologue of Ran/TC4 GTP-Binding Protein from Plasmodium falciparum
In our effort to identify and study proteins that are important for the progression of the malaria parasite, Plasmodium falciparum, through the cell cycle, we have cloned and sequenced the homologue of Ras-related nuclear protein Ran/TC4 (PfRan). The predicted peptide sequence of PfRan is 214 amino acids long and contains consensus motifs of the Ras superfamily. The expression of a 1.7 kb PfRan transcript changes during the cell cycle, reaching a peak at the trophozoite stage of growth of the parasite. The recombinant PfRan binds GTP similar to other Ras-like proteins.
- University of Florida United States
DNA, Complementary, Sequence Homology, Amino Acid, Cell Cycle, Genes, Protozoan, Molecular Sequence Data, Plasmodium falciparum, Nuclear Proteins, ran GTP-Binding Protein, GTP-Binding Proteins, Animals, Humans, Amino Acid Sequence, Cloning, Molecular, Sequence Alignment
DNA, Complementary, Sequence Homology, Amino Acid, Cell Cycle, Genes, Protozoan, Molecular Sequence Data, Plasmodium falciparum, Nuclear Proteins, ran GTP-Binding Protein, GTP-Binding Proteins, Animals, Humans, Amino Acid Sequence, Cloning, Molecular, Sequence Alignment
selected citations These citations are derived from selected sources.This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).15 popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.Average influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).Top 10% impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.Top 10%
Citations provided by BIP!Popularity provided by BIP!