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World Journal of Otorhinolaryngology-Head and Neck Surgery
Article . 2023 . Peer-reviewed
License: CC BY NC
Data sources: Crossref
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PubMed Central
Conference object . 2023
License: CC BY NC
Data sources: PubMed Central
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Eosinophil extracellular traps in respiratory ailment: Pathogenic mechanisms and clinical translation

Authors: Shun‐Yu Wu; Bo‐Yu Cai; Tian‐Yu Wang; Zhi‐Wen Cao; Hu Peng; Huan‐Hai Liu;

Eosinophil extracellular traps in respiratory ailment: Pathogenic mechanisms and clinical translation

Abstract

AbstractBackgroundEosinophilic extracellular traps (EETs) are reticular complexes comprising deoxyribonucleic‐Acid (DNA) fibers and granule proteins.AimsEETs play a crucial role in antimicrobial host responses and are pathogenic when overproduced or under degraded. EETs created by eosinophils appear to enable vital immune responses against extra‐cellular pathogens, nevertheless, trap overproduction is evident in pathology.Materials & MethodsAs considerably research is performed, new data affirmed that EETs can alter the outcome of respiratory ailment.ResultsWe probe into the disclosure and specificity of EETs produced in reaction to various stimuli and propose a role for those frameworks in ailment pathogenesis and the establishment of chronic, unresolved inflammation.DiscussionWhether EETs can be used as a prospective brand‐new target for the diagnosis, treatment and prognosis of respiratory ailments is a scientific theme worth studying.ConclusionWe probe into the disclosure and specificity of EETs produced in reaction to various stimuli and propose a role for those frameworks in ailment pathogenesis and the establishment of chronic, unresolved inflammation.

Related Organizations
Keywords

degranulation, RD1-811, Review Article, Otorhinolaryngology, RF1-547, cytolysis, Surgery, eosinophils, eosinophil extracellular traps, respiratory ailments

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    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    3
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Average
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Average
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
3
Top 10%
Average
Average
Green
gold