Teratogenic effects of ochratoxin A in mice
Copyright policy )Teratogenic effects of ochratoxin A in mice
AbstractTreatment of pregnant mice ip with 5 mg/kg ochratoxin A on one of gestation days 7–12 resulted in increased prenatal mortality, decreased fetal weight (with the exception of those treated on day 9), and various fetal malformations. Exencephaly and anomalies of the eyes, face, digits, and tail were the most common defects. The most severe malformations were complete median facial clefts associated with exencephaly and eye defects. Skeletal defects also were noted involving the ribs, vertebrae, and skull.
- Alabama Agricultural and Mechanical University United States
- University of Alabama - USA United States
Limb Deformities, Congenital, Abnormalities, Drug-Induced, Brain, Ochratoxins, Mice, Fetus, Pregnancy, Face, Animals, Pregnancy, Animal, Female, Eye Abnormalities
Limb Deformities, Congenital, Abnormalities, Drug-Induced, Brain, Ochratoxins, Mice, Fetus, Pregnancy, Face, Animals, Pregnancy, Animal, Female, Eye Abnormalities
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