
doi: 10.1002/tcr.20144
pmid: 18563806
AbstractDiversity‐oriented synthesis (DOS), which describes the synthesis of structurally diverse collections of small molecules, was developed, in part, to address combinatorial chemistry's shortfalls. In this paper, we hope to give an indication of what can be achieved using the DOS approach to library generation. We describe some of the most successful strategies utilized in DOS, with special focus on our own area of interest; DOS from simple, pluripotent starting materials. © 2008 The Japan Chemical Journal Forum and Wiley Periodicals, Inc. Chem Rec 8: 129–142; 2008: Published online in Wiley InterScience (www.interscience.wiley.com) DOI 10.1002/tcr.20144
Models, Chemical, Pharmaceutical Preparations, Chemistry, Pharmaceutical, Chemistry, Organic, Combinatorial Chemistry Techniques
Models, Chemical, Pharmaceutical Preparations, Chemistry, Pharmaceutical, Chemistry, Organic, Combinatorial Chemistry Techniques
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