The special issue Architecture, Design and Planning towards Sustainable Development: Regional Approaches, discusses how the shaping of the built environment may contribute to sustainability and resilience. It encompasses both macro and micro design by bringing together articles which deal with urban planning, architecture and product design, this way contributing to a holistic perspective of the theme. It pays attention to different regional approaches addressing the shape of surroundings fit for inhabitants with various cultural backgrounds, needs and aspirations. Thereby, the issue focuses on hitherto underrated topics contributing to a multiscale approach and crossed culture discourse.