Susceptibility of some clinical isolates of Staphylococcus aureus to bioactive column fractions from the lichen Ramalina farinacea (L.) Ach.

descriptionPublicationkeyboard_double_arrow_right Article 01 Aug 2002 English Publisher:WileyJournal:Phytotherapy Research, volume 16, pages 494-496 (issn: 0951-418X, eissn: 1099-1573,

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Authors: C O, Esimone; M U, Adikwu;

doi: 10.1002/ptr.963

pmid: 12203275

Susceptibility of some clinical isolates of Staphylococcus aureus to bioactive column fractions from the lichen Ramalina farinacea (L.) Ach.

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Abstract

AbstractThe antimicrobial activities of two bioactive column chromatographic fractions (RF1 and RF2) from the lichen Ramalina farinacea (L.) were evaluated against 15 clinical isolates of Staphylococcus aureus. The susceptibility pattern of the isolates towards tetracycline (TCN) and ampicillin (AMP) was similarly evaluated for comparison purposes. The results show that RF1 and RF2 with an MIC90 ( minimum inhibitory concentration against 90% of the isolates) of 535.5 and 317 μg/mL respectively, performed generally better than TCN and AMP with an MIC90 of 976.5 and 357 μg/mL respectively. Copyright © 2002 John Wiley & Sons, Ltd.

Related Organizations

University of Nigeria
Nigeria

Keywords

Staphylococcus aureus, Lichens, Plant Extracts, Microbial Sensitivity Tests, Penicillins, Staphylococcal Infections, Tetracycline, Anti-Bacterial Agents, Humans, Ampicillin, Macrolides

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Susceptibility of tetracycline- and ampicillin-resistant strains of Staphylococcus aureus and Salmonella typhi to bioactive column fractions from the lichen Ramalina farinacea (L.) Ach
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