Antiinflammatory activity of rotenoids from Clitoria fairchildiana
Copyright policy )Antiinflammatory activity of rotenoids from Clitoria fairchildiana
Five structurally related rotenoids were isolated from the roots of Clitoria fairchildiana. The antiinflammatory activity was investigated using a capillary permeability assay. The protective effect was measured as the inhibition in vascular permeability produced by acetic acid in the peritoneal cavity. The results suggest that for maximum activity the maintenance of the B/C ring junction integrity is important. These findings support the traditional use of Clitoria species extracts in the treatment of inflammatory conditions.
Male, Plant Extracts, Anti-Inflammatory Agents, Non-Steroidal, Fabaceae, Plant Roots, Capillary Permeability, Mice, Structure-Activity Relationship, Rotenone, Animals, Humans, Acetic Acid, Phytotherapy
Male, Plant Extracts, Anti-Inflammatory Agents, Non-Steroidal, Fabaceae, Plant Roots, Capillary Permeability, Mice, Structure-Activity Relationship, Rotenone, Animals, Humans, Acetic Acid, Phytotherapy
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