Cannabidiol in medicine: a review of its therapeutic potential in CNS disorders

descriptionPublicationkeyboard_double_arrow_right Article 09 Oct 2008 Italy English Publisher:WileyJournal:Phytotherapy Research, volume 23, pages 597-602 (issn: 0951-418X, eissn: 1099-1573,

Copyright policy )

Authors: SCUDERI, CATERINA; Daniele De Filippis; Teresa Iuvone; BLASIO, ANGELO; Antonio Steardo; ESPOSITO, GIUSEPPE;

doi: 10.1002/ptr.2625

pmid: 18844286

handle: 11588/333705 , 11573/139741

Cannabidiol in medicine: a review of its therapeutic potential in CNS disorders

- Summary
- Subjects
- Metrics

Abstract

AbstractCannabidiol (CBD) is the main non‐psychotropic component of the glandular hairs ofCannabis sativa. It displays a plethora of actions including anticonvulsive, sedative, hypnotic, antipsychotic, antiinflammatory and neuroprotective properties. However, it is well established that CBD produces its biological effects without exerting significant intrinsic activity upon cannabinoid receptors. For this reason, CBD lacks the unwanted psychotropic effects characteristic of marijuana derivatives, so representing one of the bioactive constituents ofCannabis sativawith the highest potential for therapeutic use.The present review reports the pharmacological profile of CBD and summarizes results from preclinical and clinical studies utilizing CBD, alone or in combination with other phytocannabinoids, for the treatment of a number of CNS disorders. Copyright © 2008 John Wiley & Sons, Ltd.

Country

Italy

Related Organizations

Keywords

Cannabis sativa, CNS disorder, cannabidiol, Central Nervous System Diseases, phytocannabinoid, cannabidiol; Cannabis sativa; CNS disorder; phytocannabinoid, Animals, Cannabidiol, Humans, cannabidiol; cannabis sativa; cns disorder; phytocannabinoid, Cannabis

Impact byBIP!

	selected citations These citations are derived from selected sources. This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	164
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Top 1%
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Top 10%
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Top 10%