Cytotoxic effects of the root extracts ofEurycoma longifolia Jack
Copyright policy )Cytotoxic effects of the root extracts ofEurycoma longifolia Jack
The methanol, n-butanol, chloroform and water extracts obtained from the root of Eurycoma longifolia Jack were assayed using methylene blue assay to evaluate its cytotoxic effect against KB, DU-145, RD, MCF-7, CaOV-3, MDBK cell lines. The results showed that all the root extracts except the water extract of E. longifolia produced significant cytotoxic effect on these cell lines. However, no significant cytotoxic effect was detected on MDBK (kidney) normal cell line. 9-methoxycanthin-6-one, an alkaloid, was detected in each extract with different intensities by reversed-phase high performance liquid chromatography.
- National University of Malaysia Malaysia
- Forest Research Institute Malaysia Malaysia
Methylene Blue, Lactams, Plant Extracts, Cell Line, Tumor, Humans, Eurycoma, Plant Roots, Carbolines
Methylene Blue, Lactams, Plant Extracts, Cell Line, Tumor, Humans, Eurycoma, Plant Roots, Carbolines
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