Antioxidant activity of supercritical extract of Melissa ofﬁcinalis subsp. ofﬁcinalis and Melissa ofﬁcinalis subsp. inodora

descriptionPublicationkeyboard_double_arrow_right Article 01 Oct 2004 Italy English Publisher:WileyJournal:Phytotherapy Research, volume 18, pages 789-792 (issn: 0951-418X, eissn: 1099-1573,

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Authors: Marongiu B; PORCEDDA, SILVIA; PIRAS, ALESSANDRA; ROSA, ANTONELLA; DEIANA, MONICA; Dessí MA;

doi: 10.1002/ptr.1549

pmid: 15551397

handle: 11584/107933

Antioxidant activity of supercritical extract of Melissa ofﬁcinalis subsp. ofﬁcinalis and Melissa ofﬁcinalis subsp. inodora

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Abstract

AbstractThe antioxidant activity of Melissa ofﬁcinalis subsp. ofﬁcinalis and of Melissa ofﬁcinalis subsp. inodora extracts, obtained by using carbon dioxide under supercritical conditions was investigated. The samples were prepared in two steps. A preliminary extraction at 90 bar and 50 °C eliminated the essential oil, then a further extraction at 300 bar and 50 °C obtained the high molecular mass extract. These samples were tested for autoxidation and the iron or EDTA‐mediated oxidation of linoleic acid at 37 °C in the absence of solvent, in in vitro systems. During linoleic acid autoxidation and its EDTA‐mediated oxidation both M. ofﬁcinalis and M. inodora extracts showed an antioxidant activity, and no signiﬁcant differences in their efﬁcacy were observed. None showed any prooxidant activity. Copyright © 2004 John Wiley & Sons, Ltd.

Country

Italy

Related Organizations

University of Cagliari
Italy

Keywords

Plant Extracts, Chromatography, Supercritical Fluid, Melissa, Antioxidants, Linoleic Acid, Plant Leaves, Inhibitory Concentration 50, Humans, Edetic Acid, Phytotherapy

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