Brine shrimp lethality assay of Bacopa monnieri

descriptionPublicationkeyboard_double_arrow_right Article 01 Mar 2002 English Publisher:WileyJournal:Phytotherapy Research, volume 16, pages 197-198 (issn: 0951-418X, eissn: 1099-1573,

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Authors: Prashanth, D'Souza; Mundkinajeddu, Deepak; Padmaja, Rani; Sandhya, Kadamboor; Anjana, Mathew; Arun P, Chandrashekar; Amit, Agarwal;

doi: 10.1002/ptr.1001

pmid: 11933129

Brine shrimp lethality assay of Bacopa monnieri

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Abstract

AbstractSuccessive petroleum ether, chloroform, ethanol and water extracts, a saponin rich fraction (SRF) and bacoside A isolated from Bacopa monnieri were tested for brine shrimp lethality. Successive ethanol extracts and SRF showed potent activity. Bacoside A showed the maximum activity with a LC50 of 38.3 μg/mL. The results confirmed the previous reports of an anticancer effect of Bacopa monnieri and suggest bacoside A as the active constituent. Copyright © 2002 John Wiley & Sons, Ltd.

Keywords

Lethal Dose 50, Plant Leaves, Plants, Medicinal, Plant Extracts, Animals, India, Medicine, Traditional, Artemia

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