
Abstract Structures of seven CASP14 targets were determined using cryo‐electron microscopy (cryo‐EM) technique with resolution between 2.1 and 3.8 Å. We provide an evaluation of the submitted models versus the experimental data (cryo‐EM density maps) and experimental reference structures built into the maps. The accuracy of models is measured in terms of coordinate‐to‐density and coordinate‐to‐coordinate fit. A‐posteriori refinement of the most accurate models in their corresponding cryo‐EM density resulted in structures that are close to the reference structure, including some regions with better fit to the density. Regions that were found to be less “refineable” correlate well with regions of high diversity between the CASP models and low goodness‐of‐fit to density in the reference structure.
Models, Molecular, model evaluation, 570, Bioinformatics, Protein Conformation, Mathematical sciences, Mathematical Sciences, Models, Sequence Analysis, Protein, Information and Computing Sciences, Research Articles, info:eu-repo/classification/ddc/570, electron microscopy, Protein, Cryoelectron Microscopy, Molecular, Computational Biology, Proteins, Biological Sciences, protein structure prediction, Biological sciences, CASP, cryo-EM, Sequence Analysis, Software
Models, Molecular, model evaluation, 570, Bioinformatics, Protein Conformation, Mathematical sciences, Mathematical Sciences, Models, Sequence Analysis, Protein, Information and Computing Sciences, Research Articles, info:eu-repo/classification/ddc/570, electron microscopy, Protein, Cryoelectron Microscopy, Molecular, Computational Biology, Proteins, Biological Sciences, protein structure prediction, Biological sciences, CASP, cryo-EM, Sequence Analysis, Software
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