AbstractObjectiveOutcomes from in vitro fertilization (IVF)/intrauterine insemination (ICSI) cycles for patients who underwent preimplantation genetic testing for monogenic/single gene (PGT‐M) and structural chromosome rearrangements (PGT‐SR) patients were reviewed. Patients pursuing PGT‐M and PGT‐SR often do not have pre‐existing fertility issues and therefore may have uncertain expectations of successful outcomes. Before pursuing PGT‐M and PGT‐SR, patients require evidence‐based counseling regarding the probability of having a healthy child.MethodRetrospective review from a single private IVF clinic of 73 PGT patients, from whom a total of 437 blastocysts were biopsied and screened. Embryo results and pregnancy outcomes were analyzed.ResultsOf the 45 PGT‐M patients, 64.4% had at least one euploid unaffected embryo. The cumulative pregnancy rate for patients who had embryo transfers in this group was 89.7%, with an ongoing pregnancy or delivery rate of 48.9%. For the 28 PGT‐SR patients, 60.7% had at least one euploid unaffected embryo. The cumulative pregnancy rate for patients who had embryo transfers in this group was 87.5%, with an ongoing pregnancy or delivery rate of 42.9%.ConclusionThis information can supplement the existing data in the literature to counsel new patients in terms of realistic expectations of success following PGT‐M and PGT‐SR.