Asymptomatic child heterozygous for hemoglobin S and hemoglobin Pôrto Alegre
Copyright policy )Asymptomatic child heterozygous for hemoglobin S and hemoglobin Pôrto Alegre
AbstractHemoglobin Pôrto Alegre (PA) is a rare hemoglobin resulting from a mutation in β9(A6)Ser → Cys. We describe an asymptomatic Puerto Rican female with combined heterozygosity for Hb PA and Hb S. Since birth, she has maintained normal hemoglobin, bilirubin, LDH levels, and reticulocyte count. Peripheral smear evaluation has revealed normal erythrocyte morphology with no changes suggestive of hemolysis. We conclude that the presence of Hb PA does not increase the risk of red blood cell sickling in patients who carry the Hb S mutation. Pediatr Blood Cancer 2011;56:458–459. © 2010 Wiley‐Liss, Inc.
- University of Puerto Rico System United States
Heterozygote, Erythrocytes, Hemoglobins, Abnormal, Hemoglobin, Sickle, Infant, Newborn, DNA, Prognosis, Polymerase Chain Reaction, Reticulocyte Count, Mutation, Humans, Female
Heterozygote, Erythrocytes, Hemoglobins, Abnormal, Hemoglobin, Sickle, Infant, Newborn, DNA, Prognosis, Polymerase Chain Reaction, Reticulocyte Count, Mutation, Humans, Female
selected citations These citations are derived from selected sources.This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).1 popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.Average influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).Average impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.Average
Citations provided by BIP!Popularity provided by BIP!