AbstractThe purpose of this article is twofold. We first develop the first‐order necessary optimality conditions for a general constrained fractional optimal control problem using calculus of variation. These conditions are of the form of fractional ordinary differential equations which reduce to the conventional Euler–Lagrange equations when the dynamical system becomes a first‐order one. Then, we prove, via the optimality conditions established, that a popular penalty method used for conventional constrained optimal control and optimization is an “exact” penalty method for the fractional control problem by showing that an optimal solution to the penalized problem satisfies the optimality conditions of the original one when the penalty parameter is sufficiently large. An example is also provided to verify the necessary optimality conditions.