Dendritic spine morphogenesis and plasticity
Copyright policy )Dendritic spine morphogenesis and plasticity
AbstractDendritic spines are small protrusions off the dendrite that receive excitatory synaptic input. Spines vary in size, likely correlating with the strength of the synapses they form. In the developing brain, spines show highly dynamic behavior thought to facilitate the formation of new synaptic contacts. Recent studies have illuminated the numerous molecules regulating spine development, many of which converge on the regulation of actin filaments. In addition, interactions with glial cells are emerging as important regulators of spine morphology. In many cases, spine morphogenesis, plasticity, and maintenance also depend on synaptic activity, as shown by recent studies demonstrating changes in spine dynamics and maintenance with altered sensory experience. © 2005 Wiley Periodicals, Inc. J Neurobiol 64: 47–57, 2005
- Brown University United States
- Philadelphia College of Osteopathic Medicine United States
actin filament, glutamate receptor, Neuronal, Cell Adhesion Molecules, Neuronal, Dendritic Spines, Models, Neurological, review, morphogenesis, Nerve Tissue Proteins, Multi-photon microscopy, cell motility, sex hormone, nerve ending, Models, Receptors, Morphogenesis, Animals, cell interaction, nerve cell growth, glia cell, Monomeric GTP-Binding Proteins, nonhuman, Neuronal Plasticity, dendritic spine, Neuroscience and Neurobiology, excitation, guanosine triphosphatase, nerve cell plasticity, protein function, Synapse, n methyl dextro aspartic acid receptor, ephrin, priority journal, Receptors, Glutamate, Neurological, Synapses, microscopy, Steroids, receptor intrinsic activity, Synaptogenesis, Glutamate, cell adhesion molecule, Cell Adhesion Molecules, Ephrins, Neuroglia, cell structure, hormone action
actin filament, glutamate receptor, Neuronal, Cell Adhesion Molecules, Neuronal, Dendritic Spines, Models, Neurological, review, morphogenesis, Nerve Tissue Proteins, Multi-photon microscopy, cell motility, sex hormone, nerve ending, Models, Receptors, Morphogenesis, Animals, cell interaction, nerve cell growth, glia cell, Monomeric GTP-Binding Proteins, nonhuman, Neuronal Plasticity, dendritic spine, Neuroscience and Neurobiology, excitation, guanosine triphosphatase, nerve cell plasticity, protein function, Synapse, n methyl dextro aspartic acid receptor, ephrin, priority journal, Receptors, Glutamate, Neurological, Synapses, microscopy, Steroids, receptor intrinsic activity, Synaptogenesis, Glutamate, cell adhesion molecule, Cell Adhesion Molecules, Ephrins, Neuroglia, cell structure, hormone action
selected citations These citations are derived from selected sources.This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).125 popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.Top 10% influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).Top 10% impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.Top 1%
Citations provided by BIP!Popularity provided by BIP!