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Magnetic Resonance in Medicine
Article . 2019 . Peer-reviewed
License: CC BY
Data sources: Crossref
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Magnetic Resonance in Medicine
Article
License: CC BY
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Perturbed spiral real‐time phase‐contrast MR with compressive sensing reconstruction for assessment of flow in children

Authors: Grzegorz Tomasz Kowalik; Daniel Knight; Jennifer Anne Steeden; Vivek Muthurangu;

Perturbed spiral real‐time phase‐contrast MR with compressive sensing reconstruction for assessment of flow in children

Abstract

Purposewe implemented a golden‐angle spiral phase contrast sequence. A commonly used uniform density spiral and a new ‘perturbed’ spiral that produces more incoherent aliases were assessed. The aim was to ascertain whether greater incoherence enabled more accurate Compressive Sensing reconstruction and superior measurement of flow and velocity.MethodsA range of ‘perturbed’ spiral trajectories based on a uniform spiral trajectory were formulated. The trajectory that produced the most noise‐like aliases was selected for further testing. For in‐silico and in‐vivo experiments, data was reconstructed using total Variation L1 regularisation in the spatial and temporal domains. In‐silico, the reconstruction accuracy of the ‘perturbed’ golden spiral was compared to uniform density golden‐angle spiral. For the in‐vivo experiment, stroke volume and peak mean velocity were measured in 20 children using ‘perturbed’ and uniform density golden‐angle spiral sequences. These were compared to a reference standard gated Cartesian sequence.ResultsIn‐silico, the perturbed spiral acquisition produced more accurate reconstructions with less temporal blurring (NRMSE ranging from 0.03 to 0.05) than the uniform density acquisition (NRMSE ranging from 0.06 to 0.12). This translated in more accurate results in‐vivo with no significant bias in the peak mean velocity (bias: −0.1, limits: −4.4 to 4.1 cm/s;P= 0.98) or stroke volume (bias: −1.8, limits: −9.4 to 5.8 ml,P= 0.19).ConclusionWe showed that a ‘perturbed’ golden‐angle spiral approach is better suited to Compressive Sensing reconstruction due to more incoherent aliases. This enabled accurate real‐time measurement of flow and peak velocity in children.

Keywords

Image Interpretation, Computer-Assisted, Humans, Microscopy, Phase-Contrast, Child, Data Compression

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
19
Top 10%
Top 10%
Top 10%
hybrid