AbstractTraditional methods for magnetic resonance angiography (MRA) involve the radiofrequency excitation of vascular spins within a selected region of tissue, followed by gradient localization and imaging of those spins within that same region. Signals that unfaithfully localize within the imaging volume, so‐called “ghost artifacts”, have historically been considered undesirable since they degrade image quality and every effort is made to suppress them. To the contrary, we hypothesized that these ghost artifacts could be manipulated to create detailed angiograms of the human body. In this initial demonstration of the method, which we call “Ghost MRA,” we show that the human arterial system can be depicted with exquisite anatomic detail and near total suppression of background signal. Moreover, unlike alternative unenhanced methods, Ghost MRA can be acquired without the need for cardiac synchronization. Magn Reson Med, 2009. © 2009 Wiley‐Liss, Inc.