AbstractCurved slice imaging based on multidimensional RF pulses is introduced and discussed. This new approach makes it possible to image curved anatomical structures by using MRI. The 2D RF or 3D RF pulses used can be tailored to excite or refocus transverse magnetization of a previously defined arbitrarily curved slice profile in a 3D space. These RF pulses can be integrated into all standard MRI sequences to perform slice selection. The final curved slice image is obtained as a projection of the curved slice magnetization onto a selected imaging plane. The problem of ambiguities arising due to this projection process is addressed. Phantom and in vivo experiments were performed to illustrate the advantages and limitations of this approach.