Determination of optimal angles for variable nutation proton magnetic spin‐lattice, T1, and spin‐spin, T2, relaxation times measurement
Copyright policy )Determination of optimal angles for variable nutation proton magnetic spin‐lattice, T1, and spin‐spin, T2, relaxation times measurement
AbstractT1 and T2 can be rapidly determined with a combination of multiangle spoiled gradient recalled echo (SPGR) and steady‐state free precession (SSFP) imaging. Previously, we demonstrated a simple method for determining the set of SPGR and SSFP angles that provided greater T1 and T2 precision than a set of uniformly spaced angles. In this article a more rigorous approach for determining angles is described. Weighted least‐squares is also introduced for T1 and T2 estimation and a novel weighting function described. This new approach, suited for imaging applications where large T1 and T2 ranges are anticipated, provides high and uniform precision over a wide range of T1 and T2 values. Magn Reson Med 51:194–199, 2004. © 2003 Wiley‐Liss, Inc.
- Western University Canada
- Robarts Research Institute Canada
- Robarts Research Institute, London, Canada Canada
- King's College London United Kingdom
- Kings College London, University of London United Kingdom
570, 610, Brain, Humans, Computer Simulation, Least-Squares Analysis, Models, Theoretical, Protons, Magnetic Resonance Imaging, Algorithms
570, 610, Brain, Humans, Computer Simulation, Least-Squares Analysis, Models, Theoretical, Protons, Magnetic Resonance Imaging, Algorithms
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