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Movement Disorders
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PubMed Central
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Movement Disorders
Article . 2013 . Peer-reviewed
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Movement Disorders
Other literature type . 2014
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Tremor of the eyes, or of the head, in Parkinson's disease?

Authors: Leigh, R John; Martinez-Conde, Susana;

Tremor of the eyes, or of the head, in Parkinson's disease?

Abstract

Recently, Gitchel et al.1 reported that “pervasive ocular tremor” is present in patients with Parkinson's disease (PD) while they attempt steady visual fixation. This was a universal finding in the 112 PD patients that they studied, but was generally absent from their 60 healthy control subjects. This finding of a pervasive ocular tremor in PD has generated substantial interest but also controversy, as is evident by the article by Kaski et al.,2 and the ensuing correspondence by Baron et al.3. Because pervasive ocular tremor might provide a most useful biomarker for PD, it seems justified to examine the validity of the measurements of Gitchel et al.1 and consider alternative explanations for their results, before they gain wide acceptance and application. Here we summarize some of the evidence for and against the case for pervasive ocular tremor in PD, and suggest future experiments to resolve conflicting opinions.

Keywords

Male, Tremor, Editorials, Oculomotor Nerve Diseases, Humans, Female, Parkinson Disease

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
16
Average
Top 10%
Top 10%
Green
bronze