Impulsive and compulsive behaviors in Parkinson's disease
Copyright policy )Impulsive and compulsive behaviors in Parkinson's disease
AbstractAntiparkinson therapy can be the primary cause of a range of nonmotor symptoms that include a set of complex disinhibitory psychomotor pathologies and are linked by their repetitive, reward or incentive‐based natures. These behaviors relate to aberrant or excessive dopamine receptor stimulation and encompass impulse control disorders (ICDs), punding, and the dopamine dysregulation syndrome (DDS). Common ICDs include pathological gambling, hypersexuality, compulsive eating, and compulsive buying. This review focuses on the phenomenology, epidemiology, and methods to identify and rate these disorders. The management of dopaminergic drug‐related compulsive behaviors is discussed in the light of the current understanding of the neurobiological substrate of these disorders. © 2009 Movement Disorder Society
- University Health Network Canada
- Duke University United States
- Toronto Western Hospital Canada
- Centre for Addiction and Mental Health Canada
- University of Pennsylvania United States
Male, Deep Brain Stimulation, Dopamine, Sexual Behavior, Parkinson Disease, Antiparkinson Agents, Reward, Dopamine Agonists, Gambling, Impulsive Behavior, Compulsive Behavior, Limbic System, Prevalence, Humans, Female, Disease Susceptibility, Stereotyped Behavior
Male, Deep Brain Stimulation, Dopamine, Sexual Behavior, Parkinson Disease, Antiparkinson Agents, Reward, Dopamine Agonists, Gambling, Impulsive Behavior, Compulsive Behavior, Limbic System, Prevalence, Humans, Female, Disease Susceptibility, Stereotyped Behavior
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