Carotid intima‐media thickness in Parkinson's disease

descriptionPublicationkeyboard_double_arrow_right Article 15 Dec 2007 English Publisher:WileyJournal:Movement Disorders, volume 22, pages 2,446-2,449 (issn: 0885-3185, eissn: 1531-8257,

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Authors: Jong-Moon, Lee; Kun-Woo, Park; Woo-Keun, Seo; Moon Ho, Park; Changsu, Han; Inho, Jo; Sangmee, Ahn Jo;

doi: 10.1002/mds.21757

pmid: 17960813

Carotid intima‐media thickness in Parkinson's disease

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Abstract

AbstractThere have been a few studies and inconsistent results regarding the coincidence of Parkinson's disease (PD) and atherosclerotic diseases, such as cerebrovascular disease. Carotid intima‐media thickness (IMT) is a known marker for subclinical atherosclerosis. The aim of this study was to investigate the carotid IMT between PD patients and controls. We studied 43 patients with PD and 86 matched controls. The carotid IMT in PD patients was significantly smaller than in controls (0.796 ± 0.179 mm vs. 0.913 ± 0.237 mm, P < 0.05). In multivariate analysis, the carotid IMT was inversely associated with the duration of levodopa medication and the severity of PD. These results suggest that PD patients have a lower risk of atherosclerosis. © 2007 Movement Disorder Society

Related Organizations

Korea University
Korea (Republic of)
Korea National Institute of Health
Korea (Republic of)
Ewha Womans University
Korea (Republic of)

Keywords

Male, Analysis of Variance, Parkinson Disease, Middle Aged, Risk Assessment, Antiparkinson Agents, Levodopa, Carotid Arteries, Cardiovascular Diseases, Humans, Female, Aged, Ultrasonography

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