
AbstractWe report on a 30‐year‐old patient with advanced cerebellar degeneration due to SCA2. He presented with severe myoclonus, which was resistant to conventional therapy and dramatically improved after administration of 12–18 gm/die piracetam. Piracetam may be considered in the treatment of refractory myoclonus in spinocerebellar degenerations. © 2005 Movement Disorder Society
Adult, Gait Ataxia, Male, Myoclonus, Adult, Ataxia; drug therapy/genetics, Dose-Response Relationship; Drug, Gait Ataxia; drug therapy/genetics, Humans, Infusions; Intravenous, Male, Myoclonus; drug therapy/genetics, Nerve Tissue Proteins; genetics, Neurologic Examination; drug effects, Piracetam; adverse effects/therapeutic use, Recurrence, Spinocerebellar Ataxias; drug therapy/genetics, Substance Withdrawal Syndrome; diagnosis, Treatment Outcome, Trinucleotide Repeats; genetics, Infusions, diagnosis, Nerve Tissue Proteins, Dose-Response Relationship, drug therapy/genetics, Trinucleotide Repeats, Recurrence, Humans, Spinocerebellar Ataxias, genetics, Infusions, Intravenous, Neurologic Examination, Dose-Response Relationship, Drug, Piracetam, Substance Withdrawal Syndrome, adverse effects/therapeutic use, Treatment Outcome, Ataxins, drug effects, Ataxia, Drug, Intravenous
Adult, Gait Ataxia, Male, Myoclonus, Adult, Ataxia; drug therapy/genetics, Dose-Response Relationship; Drug, Gait Ataxia; drug therapy/genetics, Humans, Infusions; Intravenous, Male, Myoclonus; drug therapy/genetics, Nerve Tissue Proteins; genetics, Neurologic Examination; drug effects, Piracetam; adverse effects/therapeutic use, Recurrence, Spinocerebellar Ataxias; drug therapy/genetics, Substance Withdrawal Syndrome; diagnosis, Treatment Outcome, Trinucleotide Repeats; genetics, Infusions, diagnosis, Nerve Tissue Proteins, Dose-Response Relationship, drug therapy/genetics, Trinucleotide Repeats, Recurrence, Humans, Spinocerebellar Ataxias, genetics, Infusions, Intravenous, Neurologic Examination, Dose-Response Relationship, Drug, Piracetam, Substance Withdrawal Syndrome, adverse effects/therapeutic use, Treatment Outcome, Ataxins, drug effects, Ataxia, Drug, Intravenous
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