Powered by OpenAIRE graph
Found an issue? Give us feedback
image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ JEADV Clinical Pract...arrow_drop_down
image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
JEADV Clinical Practice
Article . 2026 . Peer-reviewed
License: CC BY
Data sources: Crossref
image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
versions View all 2 versions
addClaim

Surgical Procedures and Medical Treatments Among Patients With Hidradenitis Suppurativa Before and After Referral to Specialised Dermatological Hospital Care: A Nationwide Registry Study

Authors: Nana A. L. Rosenø; Nadja Højgaard Pedersen; Yvonne Geissbühler; Nikolaj Holgersen; Valdemar Wendelboe Nielsen; Jacob P. Thyssen; Alexander Egeberg; +2 Authors

Surgical Procedures and Medical Treatments Among Patients With Hidradenitis Suppurativa Before and After Referral to Specialised Dermatological Hospital Care: A Nationwide Registry Study

Abstract

ABSTRACT Background Hidradenitis suppurativa (HS) is difficult to manage, in part because time to diagnosis is often long. Little is known about how referral of HS patients to specialised care impacts patterns of surgical procedures and drug prescriptions. Objectives To examine surgical procedures and medical treatments of HS patients before and after referral to specialised dermatological hospital care. Methods Using the Danish nationwide registries, all patients with a dermatologist‐verified hospital‐diagnosis of HS from the period 1 January 2000 to 31 December 2020 were identified, and information on all their skin specific surgical procedures and medical prescriptions in the period 1 January 1994 to 31 December 2021 were analysed. Results A total of 10,196 patients were included; 69.9% female; mean age 38.8 (SD 13.5) years at time of first hospital consultation. The frequency of skin specific surgical procedures increased from 10.9% to 22.0% in the year before referral compared to the year after. Also, the use of HS specific topical prescriptions (clindamycin and azelaic acid) and oral antibiotics (tetracyclines and rifampicin/clindamycin) increased, respectively, from 14.8% to 29.1%, and from 17.1% to 25.9%, whereas the use of non‐HS specific oral antibiotics decreased from 70.9% to 61.8%. A total of 341 patients were initiated on adalimumab representing an increase from 0.07% to 0.9% before to after referral. Patients on adalimumab followed similar procedural and drug utilisation patterns but had consistently higher usage of all skin specific surgical procedures and drug prescriptions, before and after referral, compared to patients not treated with biologics. Conclusions After referral to specialised dermatological hospital care, surgical procedures and drug prescriptions increased. Within the cohort of patients treated with adalimumab, initiation of biologic therapy was associated with a reduced need for other HS‐specific treatments and surgeries, indicating improved disease control. Earlier diagnosis and referral of HS patients to specialised care is warranted to improve patient outcomes. To this end, enhancing the education of non‐dermatology physicians may be instrumental in facilitating earlier recognition and referral, thereby contributing to more timely and accurate diagnosis.

Country
Denmark
Keywords

patient journey, hidradenitis suppurativa, medical prescriptions, diagnostic delay, surgical procedures

  • BIP!
    Impact byBIP!
    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    0
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Average
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Average
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Average
Powered by OpenAIRE graph
Found an issue? Give us feedback
selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
Green
gold