Tumor microenvironment and progression
Copyright policy )Tumor microenvironment and progression
AbstractTumor blood vessels are heterogeneous, of at least six distinct types, are induced primarily by vascular endothelial growth factor‐A (VEGF‐A), and provide a potentially useful therapeutic target. Breast cancer is characterized by changes in the microenvironment that result in altered tensional homeostasis. Also, breast cancers arise as the result of epigenetic as well as genetic changes. Tumor blood vessel pericytes result, in part, from bone marrow precursor cells, and VEGF is a negative regulator of glioblastoma tumor cell invasion. J. Surg. Oncol. 2011;103:468–474. © 2011 Wiley‐Liss, Inc.
- Center for Vascular Biology Research United States
- Harvard University United States
- University of California, San Francisco United States
- Beth Israel Deaconess Medical Center United States
- University of California System United States
Vascular Endothelial Growth Factor A, mechano-biology, Oncology and Carcinogenesis, Immunology, 610, Angiogenesis Inhibitors, Breast Neoplasms, angiogenesis, Rare Diseases, Neoplasms, Breast Cancer, Genetics, Tumor Microenvironment, 2.1 Biological and endogenous factors, Humans, Neoplasm Invasiveness, Oncology & Carcinogenesis, Molecular Targeted Therapy, Neovascularization, Cancer, Pathologic, patterning, Biomedical and Clinical Sciences, Neovascularization, Pathologic, Oncology and carcinogenesis, Brain Disorders, Brain Cancer, Disease Progression, Women's Health, Female
Vascular Endothelial Growth Factor A, mechano-biology, Oncology and Carcinogenesis, Immunology, 610, Angiogenesis Inhibitors, Breast Neoplasms, angiogenesis, Rare Diseases, Neoplasms, Breast Cancer, Genetics, Tumor Microenvironment, 2.1 Biological and endogenous factors, Humans, Neoplasm Invasiveness, Oncology & Carcinogenesis, Molecular Targeted Therapy, Neovascularization, Cancer, Pathologic, patterning, Biomedical and Clinical Sciences, Neovascularization, Pathologic, Oncology and carcinogenesis, Brain Disorders, Brain Cancer, Disease Progression, Women's Health, Female
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