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Research Synthesis Methods
Article . 2017 . Peer-reviewed
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Research Synthesis Methods
Article
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Apollo
Article . 2017
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PubMed Central
Other literature type . 2017
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Apollo
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UCL Discovery
Article . 2017
Data sources: UCL Discovery
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Power analysis for random‐effects meta‐analysis

Authors: Dan Jackson; Rebecca Turner;

Power analysis for random‐effects meta‐analysis

Abstract

One of the reasons for the popularity of meta‐analysis is the notion that these analyses will possess more power to detect effects than individual studies. This is inevitably the case under a fixed‐effect model. However, the inclusion of the between‐study variance in the random‐effects model, and the need to estimate this parameter, can have unfortunate implications for this power. We develop methods for assessing the power of random‐effects meta‐analyses, and the average power of the individual studies that contribute to meta‐analyses, so that these powers can be compared. In addition to deriving new analytical results and methods, we apply our methods to 1991 meta‐analyses taken from the Cochrane Database of Systematic Reviews to retrospectively calculate their powers. We find that, in practice, 5 or more studies are needed to reasonably consistently achieve powers from random‐effects meta‐analyses that are greater than the studies that contribute to them. Not only is statistical inference under the random‐effects model challenging when there are very few studies but also less worthwhile in such cases. The assumption that meta‐analysis will result in an increase in power is challenged by our findings.

Country
United Kingdom
Related Organizations
Keywords

Models, Statistical, Bias, Databases, Factual, Meta-Analysis as Topic, power calculations, cochrane, random-effects meta-analysis, Humans, Original Articles, empirical evaluation

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    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    501
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
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    influence
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
501
Top 0.1%
Top 1%
Top 0.1%
Green
hybrid