
pmid: 18147975
A method is described by which the total sabadilla alkaloids were extracted from the seed and by which a partial separation of the crude alkaloidal mixture into four crude fractions was accomplished. Extraction of the seed with Skelly B removed the oil almost completely, in amounts up to 20 per cent, together with alkaloidal Fraction A, which was shaken out of the Skelly extract with acid. Extraction of the defatted seed with alcohol removed the remaining alkaloids. Concentration of this extract to a syrup and pouring into cold water yielded a precipitate of Fraction B which contained a considerable amount of alkaloid along with nonalkaloidal matter, probably resin. The filtrate from Fraction B, upon being made alkaline with ammonia, deposited Fraction C, which was removed by filtration. Chloroform extraction of the filtrate from C yielded Fraction D. From 15.5 Kg. of seed the following approximate amounts of the above fractions were obtained: A, 152 Gm.; B, 800 Gm.; C, 220 Gm.; D, 168 Gm.
Magnoliopsida, Alkaloids, Organic Chemicals
Magnoliopsida, Alkaloids, Organic Chemicals
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