Quantitative in Vivo Iontophoretic Studies
Copyright policy )Quantitative in Vivo Iontophoretic Studies
An experimental methodology was developed to evaluate the physicochemical basis for in vitro-in vivo correlations in iontophoretic delivery situations. This experimental methodology can be used to quantitatively evaluate the extent of interaction between chemical permeation enhancers and iontophoresis for drug delivery. The inherent advantages of using Ag/AgCl electrodes are fully exploited to control pH and minimize depletion of permeant during prolonged periods of iontophoresis.
- University of Utah United States
Male, Mice, Mice, Hairless, Animals, Tetraethylammonium, Hydrogen-Ion Concentration, Iontophoresis, Tetraethylammonium Compounds, Skin
Male, Mice, Mice, Hairless, Animals, Tetraethylammonium, Hydrogen-Ion Concentration, Iontophoresis, Tetraethylammonium Compounds, Skin
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