
pmid: 2273461
Ketoprofen was assayed in tissues of surgical patients after mechanical grinding of the tissue in liquid nitrogen; the fine powder obtained allowed the drug to be determined by HPLC in the same way as for liquid samples. The method was applied to the study of ketoprofen diffusion into the tonsillar tissue of 15 patients after a single intramuscular injection of ketoprofen (100 mg). A correction was made for blood contamination after hemoglobin determination.
Adult, Male, Adolescent, Palatine Tonsil, Middle Aged, Injections, Intramuscular, Diffusion, Hemoglobins, Ketoprofen, Humans, Female, Chromatography, High Pressure Liquid
Adult, Male, Adolescent, Palatine Tonsil, Middle Aged, Injections, Intramuscular, Diffusion, Hemoglobins, Ketoprofen, Humans, Female, Chromatography, High Pressure Liquid
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