Resolution of (±)‐Propranolol

descriptionPublicationkeyboard_double_arrow_right Article 01 Sep 1979 English Publisher:Elsevier BVJournal:Journal of Pharmaceutical Sciences, volume 68, pages 1,181-1,182 (issn: 0022-3549,

Copyright policy )

Authors: Y, Yost; J L, Holtzman;

doi: 10.1002/jps.2600680935

pmid: 501548

Resolution of (±)‐Propranolol

- Summary
- Subjects
- Metrics

Abstract

Two improvements in propranolol resolution were developed. Both the (+)- and (-)-di-(p-toluoyl)tartaric acids were used as the resolving agents. This procedure reduced the number of crystallizations needed to obtain a pure product. Furthermore, synthesis of the resolving agent was improved.

Related Organizations

University of Minnesota
United States
University of Minnesota System
United States
University of Minnesota Morris
United States
United States Department of Veterans Affairs
United States

Keywords

Stereoisomerism, Crystallization, Propranolol

Impact byBIP!

	selected citations These citations are derived from selected sources. This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	31
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Average
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Top 10%
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Average