Isolation and Characterization of a Hypoglycemic Agent from Xanthium strumarium

descriptionPublicationkeyboard_double_arrow_right Article 01 Jul 1974 English Publisher:Elsevier BVJournal:Journal of Pharmaceutical Sciences, volume 63, pages 1,166-1,167 (issn: 0022-3549,

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Authors: F P, Kupiecki; C D, Ogzewalla; F M, Schell;

doi: 10.1002/jps.2600630736

pmid: 4852580

Isolation and Characterization of a Hypoglycemic Agent from Xanthium strumarium

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Abstract

A compound isolated from seeds of Xanthium strumarium exhibited potent hypoglycemic activity in the rat. Partial characterization of the crystalline compound showed that it contains only carbon, hydrogen, oxygen, and sulfur and that the sulfur appears to be present as the sulfonate group. The agent differs from all compounds previously isolated from X. strumarium.

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Keywords

Blood Glucose, Male, Plants, Medicinal, Time Factors, Plant Extracts, Rats, Animals, Hypoglycemic Agents, Spectrophotometry, Ultraviolet, Chromatography, Thin Layer, Crystallization

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