Hydroxamic acids I: Factors affecting the stability of the hydroxamic acid-iron complex
Copyright policy )Hydroxamic acids I: Factors affecting the stability of the hydroxamic acid-iron complex
The utility of hydroxamic acid formation and subsequent iron complexation as an analytical tool for succinimide has been investigated. Several factors affecting the stability of the hydroxamic acid-ferric iron complex have been studied and critical factors in the stability of the complex have been established. Conditions for a stable complex are reported. An assay utilizing hydroxamic acid formation from succinimide has been developed and shown to be completely reproducible. Two hydroxamic acids, acetohydroxamic acid and N-hydroxysuccinamide, are shown to give stable color complexes under the recommended conditions.
- The Ohio State University United States
Chemistry, Pyrrolidines, Time Factors, Chemical Phenomena, Drug Stability, Iron, Methods, Colorimetry, Hydroxamic Acids
Chemistry, Pyrrolidines, Time Factors, Chemical Phenomena, Drug Stability, Iron, Methods, Colorimetry, Hydroxamic Acids
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