Regulation of Dissolution Rate by Pellet Geometry
Copyright policy )Regulation of Dissolution Rate by Pellet Geometry
The influence of surface configuration on the dissolution behavior of pellets suspended in a turbulent flow field has been investigated. The rate of dissolution of extruded cellulose acetate hydrogen phthalate pellets was found to be a complex function of surface geometry. The study was undertaken to determine the in vitro sustained release characteristics of pellets of a form such that their loss of effective surface area during dissolution is minimized. Factors involved in the design of such pellets are discussed and data are presented which indicate the dissolution characteristics of test forms.
- University of Minnesota United States
- University of Minnesota Morris United States
Solubility, Spectrophotometry, Surface Properties, Delayed-Action Preparations, Colorimetry, Cellulose
Solubility, Spectrophotometry, Surface Properties, Delayed-Action Preparations, Colorimetry, Cellulose
selected citations These citations are derived from selected sources.This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).32 popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.Top 10% influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).Top 1% impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.Top 10%
Citations provided by BIP!Popularity provided by BIP!