
pmid: 5657540
The hydrolysis of glutethimide (2-ethyl-2-phenyl-glutarimide) in buffered aqueous solutions in the pH range 1.5—8.0 has been studied. This region exhibited specific base catalysis. The overall rate may be expressed by the equation, rate = k ' (glutethimide) at constant pH. The energy of activation, corrected for heat of ionization of water, was calculated. A mechanism of hydrolysis is proposed.
Chemistry, Kinetics, Hot Temperature, Chemical Phenomena, Glutethimide, Chromatography, Thin Layer, Hydrogen-Ion Concentration, Chromatography, Ion Exchange
Chemistry, Kinetics, Hot Temperature, Chemical Phenomena, Glutethimide, Chromatography, Thin Layer, Hydrogen-Ion Concentration, Chromatography, Ion Exchange
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