Nonaqueous titrimetry was employed to estimate quantitatively some of the compounds which are useful in treating Parkinsonism. The method was applied to both the crystalline material and their dosage forms. This technique was found to yield results which agreed well with those obtained by either the official procedures or by methods submitted by the manufacturer. Several solvent systems were employed for the analysis of the various compounds, but either chloroform alone or a phenol—chloroform mixture was found to be almost universally applicable. Indicators were found for all the medicinal agents investigated in both of the aforementioned major solvent systems. As an additional means of quantitative assay, the amine salts were precipitated as their tetraphenylborates and the resulting derivative was then determined quantitatively by nonaqueous titrimetry.