Radiosynthesis of Dextroamphetamine-14C Sulfate

descriptionPublicationkeyboard_double_arrow_right Article 01 Nov 1965 English Publisher:Elsevier BVJournal:Journal of Pharmaceutical Sciences, volume 54, pages 1,586-1,588 (issn: 0022-3549,

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Authors: Dale Blackburn; Garth Burghard;

doi: 10.1002/jps.2600541106

Radiosynthesis of Dextroamphetamine-14C Sulfate

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Abstract

A high yield radiosynthesis of dl -amphetamine-7- 14 C was developed using 0.5 c. of benzoic-7- 14 C acid as the starting material. The dl -amphetamine-7 14 C was resolved in 84 per cent yields by the successive crystallization of d -amphetamine- 14 C d -bitartrate and l -amphetamine- 14 C l -bitartrate salts.

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Smith, Kline & French
United Kingdom

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