Colorimetric Assay of Nystatin

descriptionPublicationkeyboard_double_arrow_right Article 01 Jun 1963 English Publisher:Elsevier BVJournal:Journal of Pharmaceutical Sciences, volume 52, pages 536-538 (issn: 0022-3549,

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Authors: J C, CHANG; A B, HONIG; A T, WARREN; S, LEVINE;

doi: 10.1002/jps.2600520604

pmid: 14020052

Colorimetric Assay of Nystatin

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Abstract

A colorimetric method to assay nystatin both as powder and in pharmaceutical preparations is described. Nystatin is hydrolyzed with sodium hydroxide; the yellow color produced is extracted from a buffered solution into chloroform and measured colorimetrically. Comparison with microbiological assay is shown in a degradation experiment.

Related Organizations

University of California, Los Angeles
United States

Keywords

Nystatin, Humans, Biological Assay, Colorimetry

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