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image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Journal of Pharmaceu...arrow_drop_down
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Journal of Pharmaceutical Sciences
Article . 2003 . Peer-reviewed
License: Elsevier TDM
Data sources: Crossref
image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao
Universidade Estadual Paulista São Paulo: Repositório Institucional UNESP
Article . 2003
Data sources: Bielefeld Academic Search Engine (BASE)
Journal of Pharmaceutical Sciences
Article . 2004
Data sources: Europe PubMed Central
Journal of Pharmaceutical Sciences
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Physicochemical Properties of Sildenafil Citrate (Viagra) and Sildenafil Base

descriptionPublicationkeyboard_double_arrow_right Article 01 Oct 2003 English Publisher:Elsevier BVJournal:Journal of Pharmaceutical Sciences, volume 92, pages 2,140-2,143 (issn: 0022-3549, Copyright policy )
Authors: Melnikov, P.; Corbi, P. P.; Cuin, A.; Cavicchioli, M.; Guimaraes, W. R.;

doi: 10.1002/jps.10469

pmid: 14502553

handle: 11449/33046

Physicochemical Properties of Sildenafil Citrate (Viagra) and Sildenafil Base

Abstract

Sildenafil citrate (Viagra) [I] and sildenafil base [II] are easily and unequivocally characterized by a set of physicochemical methods that include X-ray diffractometry, infrared spectroscopy, and thermal analysis. Monoclinic lattice constants: [I]: a = 26.98 A; b = 11.95 A; c = 16.68 A; beta = 106.97 degrees. [II]: a = 8.66 A; b = 34.27 A; c = 8.93 A; beta = 96.63 degrees. Both compounds decompose at 189.4 degrees C [I] and 251.9 degrees C [II]. Densities and refractive indices are given.

Related Organizations
Keywords

Spectrophotometry, Infrared, sildenafil citrate, Citric Acid, Piperazines, Sildenafil Citrate, bioinorganic chemistry, Heating, Structure-Activity Relationship, Drug Stability, X-Ray Diffraction, sildenafil base, Purines, Thermodynamics, Sulfones, Powders, Viagra

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    		 42
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    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
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    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
42
Top 10%
Top 10%
Average
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