Metabotropic glutamate receptors: Phosphorylation and receptor signaling
Copyright policy )Metabotropic glutamate receptors: Phosphorylation and receptor signaling
AbstractMetabotropic glutamate receptors (mGluRs) play important roles in neurotransmission, neuronal development, synaptic plasticity, and neurological disorders. Recent studies have revealed a sophisticated interplay between mGluRs and protein kinases: activation of mGluRs regulates the activity of a number of kinases, and direct phosphorylation of mGluRs affects receptor signaling, trafficking, and desensitization. Here we review the emerging literature on mGluR phosphorylation, signaling, and synaptic function. © 2007 Wiley‐Liss, Inc.
- National Institute of Health Pakistan
- National Institutes of Health United States
- Korea Brain Research Institute Korea (Republic of)
- CHA University Korea (Republic of)
- Yonsei University Korea (Republic of)
synaptic plasticity, Synapses/physiology*, protein phosphatase, desensitization, 610, protein kinase, Biological, Receptors, Metabotropic Glutamate, Models, Biological, Metabotropic Glutamate/metabolism, Models, Receptors, Signal Transduction/physiology*, mGluR, Synapses, Metabotropic Glutamate/physiology*, endocytosis, Animals, Phosphorylation, Signal Transduction
synaptic plasticity, Synapses/physiology*, protein phosphatase, desensitization, 610, protein kinase, Biological, Receptors, Metabotropic Glutamate, Models, Biological, Metabotropic Glutamate/metabolism, Models, Receptors, Signal Transduction/physiology*, mGluR, Synapses, Metabotropic Glutamate/physiology*, endocytosis, Animals, Phosphorylation, Signal Transduction
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