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Journal of Neuroscience Research
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Article . 2008
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Metabotropic glutamate receptors: Phosphorylation and receptor signaling

descriptionPublicationkeyboard_double_arrow_right Article 30 Jul 2007 Korea (Republic of) Publisher:WileyJournal:Journal of Neuroscience Research, volume 86, pages 1-10 (issn: 0360-4012, eissn: 1097-4547, Copyright policy )
Authors: Jinu Lee; Katherine W. Roche; Jae-Youn Lee; Chul Hoon Kim;

doi: 10.1002/jnr.21437

pmid: 17663464

Metabotropic glutamate receptors: Phosphorylation and receptor signaling

Abstract

AbstractMetabotropic glutamate receptors (mGluRs) play important roles in neurotransmission, neuronal development, synaptic plasticity, and neurological disorders. Recent studies have revealed a sophisticated interplay between mGluRs and protein kinases: activation of mGluRs regulates the activity of a number of kinases, and direct phosphorylation of mGluRs affects receptor signaling, trafficking, and desensitization. Here we review the emerging literature on mGluR phosphorylation, signaling, and synaptic function. © 2007 Wiley‐Liss, Inc.

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Korea (Republic of)
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Keywords

synaptic plasticity, Synapses/physiology*, protein phosphatase, desensitization, 610, protein kinase, Biological, Receptors, Metabotropic Glutamate, Models, Biological, Metabotropic Glutamate/metabolism, Models, Receptors, Signal Transduction/physiology*, mGluR, Synapses, Metabotropic Glutamate/physiology*, endocytosis, Animals, Phosphorylation, Signal Transduction

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    citations
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 127
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    		 Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 Top 10%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    		 Top 10%
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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
127
Top 10%
Top 10%
Top 10%
Green
Related to Research communities
Neuroscience