
In recent years, considerable interest has developed in recognizing antigenic specificities additional to the surface antigen in the sera of patients infected with hepatitis B infection. The presence of the e-antigen appears to be invariably associated with ongoing virus replication. In the present study, sera from acute and chronically infected patients have been examined for both e-antigen and antibody, and the results correlated with the presence of complete 42-nm virus particles. In addition, some preliminary results illustrating the possible physicochemical nature of e-antigen are presented.
DNA-Directed DNA Polymerase, Hepatitis B, Hepatitis B Antigens, Molecular Weight, Viral Proteins, Acute Disease, Carrier State, Humans, Isoelectric Point, Hepatitis B Antibodies, Peptides
DNA-Directed DNA Polymerase, Hepatitis B, Hepatitis B Antigens, Molecular Weight, Viral Proteins, Acute Disease, Carrier State, Humans, Isoelectric Point, Hepatitis B Antibodies, Peptides
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