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Journal of Medical Radiation Sciences
Article . 2021 . Peer-reviewed
License: CC BY NC ND
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Journal of Medical Radiation Sciences
Article
License: CC BY NC ND
Data sources: UnpayWall
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Clinical impact of magnetic resonance imaging distortions on gamma knife radiosurgery

Authors: Sinead Jacobson; Catherine Jones; Ryan Lusk; Mike Jenkins; Crispen Chamunyonga; Mark B Pinkham; Elizabeth Brown;

Clinical impact of magnetic resonance imaging distortions on gamma knife radiosurgery

Abstract

AbstractIntroductionMagnetic resonance imaging (MRI) is the preferred imaging modality for Leksell Gamma Knife® (LGK) stereotactic radiosurgery (SRS) treatment planning (TP) due to superior soft tissue definition compared to computed tomography (CT). However, inherent distortions in MRI can affect treatment accuracy. The aim of this study was to develop a model to visualise the effect of MRI distortion on LGK SRS target coverage.MethodsA model was developed using MR images of a QUASARTM GRID3D QA phantom. One hundred and twenty‐five points were compared against known phantom geometry. Using linear interpolation, the model was applied retrospectively to 10 brain metastases patient data sets treated with LGK. The model estimated the corrected shot position accounting for distortion. A total of 44 metastases were investigated regarding the effects of MRI distortion on target coverage.ResultsThe model indicated significantly reduced mean error by 0.30 mm and variance by 0.09 mm (P = 0.008). After model application, 23 (53%) metastases showed reduced coverage. Six of the 23 metastases were deemed to be potentially clinically significant changes. Results indicated MRI distortion had a greater effect on smaller targets (mean 0.06cc) located further away from the image isocentre (mean 64.88 mm).ConclusionThis study developed a model to visualise the effect of MRI distortion on LGK SRS target coverage. Results suggest that MRI distortion can affect target coverage and the developed model may be one method to assess its impact. These results indicate that MRI distortion may have a greater effect on smaller targets located at the image periphery.

Country
Australia
Keywords

Image distortion, Phantoms, Imaging, stereotactic radiosurgery, R895-920, 610, quality assurance, Original Articles, Radiosurgery, Magnetic Resonance Imaging, Leksell Gamma Knife, Medical physics. Medical radiology. Nuclear medicine, magnetic resonance imaging, Humans, Tomography, X-Ray Computed, Retrospective Studies

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    Top 10%
    influence
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    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
7
Top 10%
Average
Top 10%
Green
gold