Macromolecular crowding and molecular recognition

descriptionPublicationkeyboard_double_arrow_right Article 01 Dec 1993 English Publisher:WileyJournal:Journal of Molecular Recognition, volume 6, pages 211-214 (issn: 0952-3499, eissn: 1099-1352,

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Authors: A P, Minton;

doi: 10.1002/jmr.300060410

pmid: 7917416

Macromolecular crowding and molecular recognition

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Abstract

AbstractThe effects of macromolecular crowding upon macromolecular associations in solution, and upon binding of a macromolecular ligand to a surface site, ar ereviewed. It is demonstrated, by means of two examples, that crowding may lead to significant alterations of biochemical or biological recognition processes at the molecular level.

Related Organizations

National Institute of Health
Pakistan
National Institute of Diabetes and Digestive and Kidney Diseases
United States
National Institutes of Health
United States

Keywords

Solutions, Binding Sites, Models, Chemical, Macromolecular Substances, Receptors, Virus, Thermodynamics, In Vitro Techniques, Ligands, Binding, Competitive, Models, Biological

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