
doi: 10.1002/jlcr.3531
pmid: 28618064
Technetium‐99m (99mTc) is a widely used radionuclide, and the development of 99mTc imaging agents continues to be in demand. This overview discusses basic principles of 99mTc radiopharmaceutical preparation and design and focuses on the 99mTc radiochemistry relevant to its pharmaceutical applications. The 99mTc complexes are described based on the most typical examples in each category, keeping up with the state‐of‐the‐art in the field. In addition, the main current strategies to develop targeted 99mTc radiopharmaceuticals are summarized.
Diagnostic Imaging, Radiochemistry, Staining and Labeling, Animals, Humans, Technetium, Radiopharmaceuticals
Diagnostic Imaging, Radiochemistry, Staining and Labeling, Animals, Humans, Technetium, Radiopharmaceuticals
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