descriptionPublicationkeyboard_double_arrow_right Article 01 Dec 1979 English Publisher:WileyJournal:Journal of Experimental Zoology, volume 210, pages 553-560 (issn: 0022-104X, eissn: 1097-010X,

Authors: Frels, W I; Chapman, V M;

doi: 10.1002/jez.1402100319

pmid: 541607

Paternal X chromosome expression in extraembryonic membranes of XO mice

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Abstract

AbstractThe paternally derived allelic form of the X chromosome linked enzyme phosphoglycerate kinase (PGK‐1) is expressed in both the fetus and extraembryonic membranes of 9.5 day post coitum XO (XPO) mouse conceptuses. Previous studies on trophectoderm and primitive endoderm derived extraembryonic membranes in XX conceptuses suggest expression of only the maternally derived X chromosome (Xm). Our results suggest that the observed lack of expression of XP in the trophectoderm and primitive endoderm derivatives of XX embryos is not an intrinsic property of the XP chromosome.

Related Organizations

Roswell Park Cancer Institute
United States
Jackson Laboratory
United States

Keywords

Sex Chromosomes, X Chromosome, Physiology:, Placenta, Congenic Resistant Lines:, Genes:, Trophoblasts, Mice, Phosphoglycerate Kinase, Phenotype, Strains:, Animals, Female, Hereditary Factors:, Alleles, Yolk Sac

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