Bromodomain‐containing protein 4 and its role in cardiovascular diseases
Copyright policy )Bromodomain‐containing protein 4 and its role in cardiovascular diseases
AbstractBromodomain‐containing protein 4 (BRD4), a chromatin‐binding protein, is involved in the development of various tumors. Recent evidence suggests that BRD4 also plays a significant role in cardiovascular diseases, such as ischemic heart disease, hypertension, and cardiac hypertrophy. This review summarizes the roles of BRD4 as a potential regulator of various pathophysiological processes in cardiovascular diseases, implicating that BRD4 may be a new therapeutic target for cardiovascular diseases in the future.
- University of South China China (People's Republic of)
- University of Calgary Canada
- Research Medical Center United States
Transcriptional Activation, Transcription, Genetic, Ventricular Remodeling, Protein Conformation, Myocardial Ischemia, Cardiomegaly, Cell Cycle Proteins, Vascular Remodeling, Bromodomain Containing Proteins, Hypertension, Humans, Transcription Factors
Transcriptional Activation, Transcription, Genetic, Ventricular Remodeling, Protein Conformation, Myocardial Ischemia, Cardiomegaly, Cell Cycle Proteins, Vascular Remodeling, Bromodomain Containing Proteins, Hypertension, Humans, Transcription Factors
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